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French Parasitology Alliance For Health Care


  JJ Lopez Rubio



microscope Laboratory of Pathogen-Host Interactions (LPHI), UMR5235 
team Plasmodium DNA biology 
location Montpellier
orcid 0000-0002-0555-1122 
email This email address is being protected from spambots. You need JavaScript enabled to view it.

Scientific interests and projects

Our team uses cutting edge technologies to understand DNA biology in Plasmodium falciparum, a unicellular eukaryotic parasite that causes the most severe form of malaria in humans. Given the tight regulation of gene expression in malaria parasites, the apparent paucity of transcription-associated factors is surprising and points to existence of divergent regulatory pathways. Our projects investigate two emerging mechanisms for gene regulation, non coding RNA and G4-quadruplex DNA secondary structures. Such divergent regulatory mechanisms present ideal drug targets that may be explored for new antimalarial strategies.