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French Parasitology Alliance For Health Care


 

  Gerald Spaeth

 

Gerald SPAETH

Information

microscope Departement of Parasite and Insect vectors 
team Molecular Parasitology and Signaling 
location Bordeaux
orcid 0000-0002-0256-2029 
email This email address is being protected from spambots. You need JavaScript enabled to view it.
website https://research.pasteur.fr/en/team/molecular-parasitology-and-signaling/

Top 5 publications of the last 5 years

1. Bussotti G et al. and Späth GF. Leishmania Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene CNV, Karyotype Instability, and Telomeric Amplification. MBio. 2018 doi: 10.1128/mBio.01399-18

2. Prieto Barja P et al. and Späth GF. Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani. Nature Ecol Evol, 2017. doi: 10.1038/s41559-017-0361-x

3. Drini S et al., and Späth GF. Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids. Genome Biol Evol. 2016. 10.1093/gbe/evw140

4. Cayla M et al. and Späth GF. Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability. PLoS Path. 2014 10.1371/journal.ppat.1004347

5. Dacher M et al. and Späth GF. Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses. Mol Microbiol. 2014 10.1111/mmi.12648