Uncategorised

List of publications

Publications since the beginning of the LabEx ParaFrap are ranked per year and per alphabetic order.

In blue, publications shared with at least two ParaFrap partners.

To access the publication, click on the doi link.

Impact factor is mentioned after each journal.

2012 ⎪ 2013 ⎪ 2014 ⎪ 2015 ⎪ 2016 ⎪ 2017 ⎪ 2018 ⎪ 2019 ⎪ 2020 ⎪ 2021 ⎪ 2022 ⎪ 2023 ⎪ 2024

2024

Alencar, M.B., Girard, R.M.B.M., Crispim, M., Baptista, C.G., Biran, M., Bringaud, F., Silber, A.M., (2024). Elucidating the Transport Mechanisms and Metabolic Roles of Serine, Threonine, and Glycine in Trypanosoma cruzi. bioRxiv [preprint] 2024.06.29.601350. doi: 10.1101/2024.06.29.601350

Antunes, A.V., Shahinas, M., Swale, C., Farhat, D.C., Ramakrishnan, C., Bruley, C., Cannella, D., Robert, M.G., Corrao, C., Couté, Y., Hehl, A.B., Bougdour, A., Coppens, I., Hakimi, M.-A., (2024). In vitro production of cat-restricted Toxoplasma pre-sexual stages. Nature [50.5] 625, 366–376. doi: 10.1038/s41586-023-06821-y

Audibert, A., Mas-Orea, X., Rey, L., Belloy, M., Bassot, E., Marodon, G., Masson, F., Cenac, N., Dietrich, G., Bonnart, C., Blanchard, N., (2024). Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling. bioRxiv [preprint] 2024.09.13.612908. doi: 10.1101/2024.09.13.612908

Baillou, A., Tomal, F., Chaumeil, T., Barc, C., Levern, Y., Sausset, A., Pezier, T., Schulthess, J., Peltier-Pain, P., Laurent, F., Lacroix-Lamandé, S., (2024). Characterization of intestinal mononuclear phagocyte subsets in young ruminants at homeostasis and during Cryptosporidium parvum infection. Front Immunol [7.3] 15. doi: 10.3389/fimmu.2024.1379798

Barrett, J.R., Silk, S.E., Mkindi, C.G., Kwiatkowska, K.M., Hou, M.M., Lias, A.M., Kalinga, W.F., Mtaka, I.M., McHugh, K., Bardelli, M., Davies, H., King, L.D.W., Edwards, N.J., Chauhan, V.S., Mukherjee, P., Rwezaula, S., Chitnis, C.E., Olotu, A.I., Minassian, A.M., Draper, S.J., Nielsen, C.M., (2024). Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens. Front Immunol [5.7] 14. doi: 10.3389/fimmu.2023.1193079/full

Belloy, M., Schmitt, B.A.M., Marty, F.H., Paut, C., Bassot-Parra, E., Amel, A., Alis, M., Ecalard, R., Boursereau, R., Gonzalez-Dunia, D., Blanchard, N., Suberbielle, E., (2024). Chronic IL-1-induced DNA double-strand break response in hippocampal neurons drives cognitive deficits. bioRxiv [preprint] 2024.02.03.578747. doi: 10.1101/2024.02.03.578747

Bitew, M.A., Gaete, P.S., Swale, C., Maru, P., Contreras, J.E., Saeij, J.P.J., (2024). Two Toxoplasma gondii putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole. mBio [6.4] 15, e03081-23. doi: 10.1128/mbio.03081-23

Cesar-Rodo, E., Dupouy, B., Häberli, C., Strub, J.-M., Williams, D.L., Mäser, P., Rottmann, M., Keiser, J., Lanfranchi, D.A., Davioud-Charvet, E., (2024). Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies. Molecules [4.2] 29, 5268. doi: 10.3390/molecules29225268

Charital, S., Lourdel, A., Quansah, N., Botté, C.Y., Yamaryo-Botté, Y., (2024a). Monitoring of Lipid Fluxes Between Host and Plastid-Bearing Apicomplexan Parasites, in: Maréchal, E. (Ed.), Plastids: Methods and Protocols [Book Chapter]. Springer US, New York, NY, pp. 197–204. doi: 10.1007/978-1-0716-3726-5_12

Charital, S., Shunmugam, S., Dass, S., Alazzi, A.M., Arnold, C.-S., Katris, N.J., Duley, S., Quansah, N.A., Pierrel, F., Govin, J., Yamaryo-Botté, Y., Botté, C.Y., (2024b). The acyl-CoA synthetase TgACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions. mBio [6.4] 0, e00427-24. doi: 10.1128/mbio.00427-24

Coulibaly, A.S.K., Nozeran, L., Thomann, C., Alis, M., Bassot, E., Hassan, A., Porte, R., Belloy, M., Blanchard, N., Masson, F., (2024). Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection. bioRxiv [preprint] 2024.07.30.605547. doi: 10.1101/2024.07.30.605547

Das, S., Unhale, T., Marinach, C., Alegria, B. del C.V., Roux, C., Madry, H., Oumoussa, B.M., Amino, R., Iwanaga, S., Briquet, S., Silvie, O., (2024). Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei. bioRxiv [preprint] 2024.10.14.618196. doi: 10.1101/2024.10.14.618196

Dass, S., Shunmugam, S., Charital, S., Duley, S., Arnold, C.-S., Katris, N.J., Cavaillès, P., Cesbron-Delauw, M.-F., Yamaryo-Botté, Y., Botté, C.Y., (2024). Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation. Journal of Lipid Research 65. doi: 10.1016/j.jlr.2024.100645

Diaz-Barreiro, A., Cereghetti, G., Sánchez, F.G.O., Tonacini, J., Talabot-Ayer, D., Kieffer-Jaquinod, S., Kissling, V.M., Huard, A., Swale, C., Knowles, T.P.J., Couté, Y., Peter, M., Francés-Monerris, A., Palmer, G., (2024). Oxidation-sensitive cysteines drive IL-38 amyloid formation. Cell Rep [7.5] 43. doi: 10.1016/j.celrep.2024.114940

Diffendall, G., Claës, A., Barcons-Simon, A., Nyarko, P., Dingli, F., Santos, M., Loew, D., Claessens, A., Scherf, A., (2024). RNA polymerase III is involved in regulating Plasmodium falciparum virulence. eLife [6.4] 13. doi: 10.7554/eLife.95879.2

Diffendall, G., Scherf, A., (2024). Deciphering the Plasmodium falciparum perinuclear var gene expression site. Trends Parasitol [7.0] 40, 707–716. doi: 10.1016/j.pt.2024.06.002

Dinamarca, S., Croce, C., Salvioni, A., Garrido, F., Fidalgo, S.E., Bigliani, G., Mayorga, L.S., Blanchard, N., Cebrian, I., (2024). SNX17 Regulates Antigen Internalisation and Phagosomal Maturation by Dendritic Cells. Immunology [4.9]. doi: 10.1111/imm.13878

Dorin-Semblat, D., Semblat, J.-P., Hamelin, R., Srivastava, A., Tetard, M., Matesic, G., Doerig, C., Gamain, B., (2024). Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. bioRxiv [preprint] 2024.07.08.602479. doi: 10.1101/2024.07.08.602479

Dupouy, B., Donzel, M., Roignant, M., Charital, S., Keumoe, R., Yamaryo-Botté, Y., Feckler, A., Bundschuh, M., Bordat, Y., Rottmann, M., Mäser, P., Botté, C.Y., Blandin, S.A., Besteiro, S., Davioud-Charvet, E., (2024a). 3-Benzylmenadiones and their Heteroaromatic Analogues Target the Apicoplast of Apicomplexa Parasites: Synthesis and Bioimaging Studies. ACS Infect Dis [4.1] 10, 3553–3576. doi: 10.1021/acsinfecdis.4c00304

Dupouy, B., Cotos, L., Binder, A., Slavikova, L., Rottmann, M., Mäser, P., Jacquemin, D., Ganter, M., Davioud‐Charvet, E., Elhabiri, M., (2024b). Click Coupling of Flavylium Dyes with Plasmodione Analogues: Towards New Redox‐Sensitive Pro‐Fluorophores. Chem-Eur J [3.9] e202403691. doi: 10.1002/chem.202403691

Dupouy, B., Karpstein, T., Häberli, C., Cal, M., Rottmann, M., Maeser, P., Keiser, J., Elhabiri, M., Davioud-Charvet, E., (2024c). Synthesis of 1,2,3‐Triazole‐Methyl‐Menadione Derivatives: Evaluation of Electrochemical and Antiparasitic Properties against two Blood‐Dwelling Parasites. ChemMedChem [3.6] e202400731. doi: 10.1002/cmdc.202400731

Gaucher, J., Montellier, E., Vial, G., Chuffart, F., Guellerin, M., Bouyon, S., Lemarie, E., Botté, Y.Y., Dirani, A., Ben Messaoud, R., Faure, M.J., Ribuot, D.G., Costentin, C., Tamisier, R., Botté, C.Y., Khochbin, S., Rousseaux, S., Pépin, J.-L., (2024). Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans. iScience [5.8] 108837. doi: 10.1016/j.isci.2024.108837

Gendron, T., Lanfranchi, D.A., Wenzel, N.I., Kessedjian, H., Jannack, B., Maes, L., Cojean, S., Müller, T.J.J., Loiseau, P.M., Davioud-Charvet, E., (2024). Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones. Molecules [4.6] 29, 1620. doi: 10.3390/molecules29071620

Gharzeddine, K., Pietro, C.G., Malier, M., Hennot, C., Grespan, R., Yamaryo-Botté, Y., Botté, C.Y., Thomas, F., Laverriere, M.-H., Girard, E., Roth, G., Millet, A., (2024). Metabolic reprogramming of hypoxic tumor-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers. bioRxiv [preprint] 2024.02.22.581558. doi: 10.1101/2024.02.22.581558

Hellani, F., Leleu, I., Saidi, N., Martin, N., Lecoeur, C., Werkmeister, E., Koffi, D., Trottein, F., Yapo-Etté, H., Das, B., Abbadie, C., Pied, S., (2024). Role of astrocyte senescence regulated by the non– canonical autophagy in the neuroinflammation associated to cerebral malaria. Brain, Behavior, and Immunity 117, 20–35. doi: 10.1016/j.bbi.2023.12.030

Iacobucci, I., Monaco, V., Hovasse, A., Dupouy, B., Keumoe, R., Cichocki, B., Elhabiri, M., Meunier, B., Strub, J.-M., Monti, M., Cianférani, S., Blandin, S.A., Schaeffer-Reiss, C., Davioud-Charvet, E., (2024). Proteomic Profiling of Antimalarial Plasmodione Using 3-Benz(o)ylmenadione Affinity-Based Probes. ChemBioChem [2.6] e202400187. doi: 10.1002/cbic.202400187

Kumar, K., Crobu, L., Sterkers, Y., Prajapati, V.K., (2024). Apoptotic proteins in Leishmania donovani: In silico screening, modelling, and validation by knock-out and gene expression analysis. bioRxiv [preprint] 2024.04.05.588228. doi: 10.1101/2024.04.05.588228

Martinez, F.J., White, M., Guillotte-Blisnick, M., Huon, C., Boucharlat, A., Agou, F., England, P., Popovici, J., Hou, M.M., Silk, S.E., Barrett, J.R., Nielsen, C.M., Reimer, J.M., Mukherjee, P., Chauhan, V.S., Minassian, A.M., Draper, S.J., Chitnis, C.E., (2024). PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. npj Vaccines [6.9] 9, 1–11. doi: 10.1038/s41541-023-00796-7

McLaughlin, E., Zavala Martinez, M.G., Dujeancourt-Henry, A., Chaze, T., Gianetto, Q.G., Matondo, M., Urbaniak, M.D., Glover, L., (2024). Phosphoproteomic analysis of the response to DNA damage in Trypanosoma brucei. Journal of Biological Chemistry 300, 107657. doi: 10.1016/j.jbc.2024.107657

Platon, L., Leroy, D., Fidock, D.A., Ménard, D., (2024). Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin. Microbiol Spectr [3.7] 0, e03500-23. doi: 10.1128/spectrum.03500-23

Porte, R., Belloy, M., Audibert, A., Bassot, E., Aïda, A., Alis, M., Miranda-Capet, R., Jourdes, A., Gisbergen, K. van, Masson, F., Blanchard, N., (2024). Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection. bioRxiv [preprint] 2024.02.08.579453. doi: 10.1101/2024.02.08.579453

Quansah, N., Sarah, C., Yamaryo-Botté, Y., Botté, C.Y., (2024). Complex Endosymbiosis II: The Nonphotosynthetic Plastid of Apicomplexa Parasites (The Apicoplast) and Its Integrated Metabolism, in: Maréchal, E. (Ed.), Plastids: Methods and Protocols [Book Chapter]. Springer US, New York, NY, pp. 43–62. doi: 10.1007/978-1-0716-3726-5_3

Seveno, M., Loubens, M.N., Berry, L., Graindorge, A., Lebrun, M., Lavazec, C., Lamarque, M.H., (2024). The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole. bioRxiv [preprint] 2024.07.30.605770. doi: 10.1101/2024.07.30.605770

Singh, P., Serizay, J., Couble, J., Cabahug, M.D., Rosa, C., Chen, P., Scherf, A., Koszul, R., Baumgarten, S., Bryant, J.M., (2024). Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite. bioRxiv [preprint] 2024.08.28.610079. doi: 10.1101/2024.08.28.610079

Thiele, P.J., Mela-Lopez, R., Blandin, S.A., Klug, D., (2024). Let it glow: genetically encoded fluorescent reporters in Plasmodium. Malar J [3.0] 23, 114. doi: 10.1186/s12936-024-04936-9

Tottey, J., Etienne-Mesmin, L., Chalançon, S., Sausset, A., Denis, S., Mazal, C., Blavignac, C., Sallé, G., Laurent, F., Blanquet-Diot, S., Lacroix-Lamandé, S., (2024). Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model. Gut Pathog [4.3] 16, 55. doi: 10.1186/s13099-024-00648-2

Trometer, N., Pecourneau, J., Feng, L., Navarro-Huerta, J.A., Lazarin-Bidóia, D., de Oliveira Silva Lautenschlager, S., Maes, L., Fortes Francisco, A., Kelly, J.M., Meunier, B., Cal, M., Mäser, P., Kaiser, M., Davioud-Charvet, E., (2024). Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. ACS Infect. Dis. doi: 10.1021/acsinfecdis.4c00137

Vigetti, L., Touquet, B., Debarre, D., Rose, T., Bureau, L., Abdallah, D., Dubacheva, G.V., Tardieux, I., (2024). Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility. Nat Microbiol 1–17. doi: 10.1038/s41564-024-01818-3

2023

Abebe, A., Bouyssou, I., Mabilotte, S., Dugassa, S., Assefa, A., Juliano, J.J., Lo, E., Menard, D., Golassa, L., (2023). Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence. PLoS Negl Trop Dis [4.8] 17, e0011326. doi: 10.1371/journal.pntd.0011326

Alloo, J., Leleu, I., Grangette, C., Pied, S., (2023). Parasite infections, neuroinflammation, and potential contributions of gut microbiota. Front Immunol [7.3] 13, 1024998. doi: 10.3389/fimmu.2022.1024998

Asencio, C., Hervé, P., Morand, P., Oliveres, Q., Morel, C.A., Prouzet-Mauleon, V., Biran, M., Monic, M., Bonhivers, M., Robinson, D.R., Ouellette, O., Riviere, L., Bringaud, F., Tetaud, E., (2023). Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania. bioRxiv [preprint] 2023.10.25.563974. doi: 10.1101/2023.10.25.563974

Baraka, V., Makenga, G., Francis, F., Kavishe, R.A., Minja, D.T., Ménard, D., (2023). PA-426 Genetic profiling of molecular markers of antimalarial resistance in areas targeted for school-based malaria chemoprevention strategies in North-Eastern, Tanzania. BMJ Glob Health [8.1] 8. doi: 10.1136/bmjgh-2023-EDC.196

Belhimeur, S., Briquet, S., Peronet, R., Pham, J., Commere, P.-H., Formaglio, P., Amino, R., Scherf, A., Silvie, O., Mecheri, S., (2023). Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity. Front Immunol [7.3] 14. doi: 10.3389/fimmu.2023.1143012

Bouyssou, I., Hoss, S.E., Doderer-Lang, C., Schoenhals, M., Rasoloharimanana, L.T., Vigan-Womas, I., Ratsimbasoa, A., Abate, A., Golassa, L., Mabilotte, S., Kessler, P., Guillotte-Blisnick, M., Martinez, F.J., Chitnis, C.E., Strouboulis, J., Ménard, D., (2023). Unveiling P. vivax invasion pathways in Duffy-negative individuals. Cell Host Microbe [31.3] 31, 2080-2092.e5. doi: 10.1016/j.chom.2023.11.007

Calvo-Alvarez, E., Ngoune, J.M.T., Sharma, P., Cooper, A., Camara, A., Travaillé, C., Crouzols, A., MacLeod, A., Rotureau, B., (2023). FLAgellum Member 8 modulates extravascular distribution of African trypanosomes. PLoS Pathog [7.4] 19, e1011220. doi: 10.1371/journal.ppat.1011220

Castellano, C.M., Lacroix, L., Mathis, E., Prorok, P., Hennion, M., Lopez-Rubio, J.-J., Méchali, M., Gomes, A.R., (2023). The genetic landscape of origins of replication in P. falciparum. Nucleic Acids Res [19.2] gkad1103. doi: 10.1093/nar/gkad1103

Chêne, A., Desrames, A., Tomlinson, A., Ruffié, C., Tangy, F., Gamain, B., (2023). An ACE2-Based Bimodular Fusion Protein Enables Reorientation of Endogenous Anti–Epstein-Barr Virus Antibodies Toward SARS-CoV-2 Spike. J Infect Dis [7.8] jiad329. doi: 10.1093/infdis/jiad329

Corucci, G., Batchu, K.C., Luchini, A., Santamaria, A., Frewein, M.P.K., Laux, V., Haertlein, M., Yamaryo-Botté, Y., Botté, C.Y., Sheridan, T., Tully, M., Maestro, A., Martel, A., Porcar, L., Fragneto, G., (2023). Developing advanced models of biological membranes with hydrogenous and deuterated natural glycerophospholipid mixtures. J Colloid Interf Sci [10.0] 645, 870–881. doi: 10.1016/j.jcis.2023.04.135

Dacheux, D., Martinez, G., Broster Reix, C.E., Beurois, J., Lores, P., Tounkara, M., Dupuy, J.-W., Robinson, D.R., Loeuillet, C., Lambert, E., Wehbe, Z., Escoffier, J., Amiri-Yekta, A., Daneshipour, A., Hosseini, S.-H., Zouari, R., Mustapha, S.F.B., Halouani, L., Jiang, X., Shen, Y., Liu, C., Thierry-Mieg, N., Septier, A., Bidart, M., Satre, V., Cazin, C., Kherraf, Z.E., Arnoult, C., Ray, P.F., Toure, A., Bonhivers, M., Coutton, C., (2023). Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function. eLife [7.7] 12, RP87698. doi: 10.7554/eLife.87698

Dechavanne, C., Dechavanne, S., Bosch, J., Metral, S., Redinger, K.R., Watson, Q.D., Ratsimbasoa, A.C., Roeper, B., Krishnan, S., Fong, R., Bennett, S., Carias, L., Chen, E., Salinas, N.D., Ghosh, A., Tolia, N.H., Woost, P.G., Jacobberger, J.W., Colin, Y., Gamain, B., King, C.L., Zimmerman, P.A., (2023). Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals. Cell Host Microbe [31.3] 31, 2093-2106.e7. doi: 10.1016/j.chom.2023.10.019

Diffendall, G., Claës, A., Barcons-Simon, A., Nyarko, P., Dingli, F., Loew, D., Claessens, A., Scherf, A., (2023). RNA polymerase III is involved in regulating Plasmodium falciparum virulence. bioRxiv [preprint] 2023.07.18.549525. doi: 10.1101/2023.07.18.549525

Dobrescu, I., Hammam, E., Dziekan, J.M., Claës, A., Halby, L., Preiser, P., Bozdech, Z., Arimondo, P.B., Scherf, A., Nardella, F., (2023). Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. ACS Infect Dis [5.3] 9, 1257–1266. doi: 10.1021/acsinfecdis.3c00127

Doritchamou, J., Nielsen, M.A., Chêne, A., Viebig, N.K., Lambert, L.E., Sander, A.F., Semblat, J.-P., Hundt, S., Orr-Gonzalez, S., Janitzek, C.M., Spiegel, A.J., Clemmensen, S.B., Thomas, M.L., Nason, M.C., Snow-Smith, M., Barnafo, E.K., Shiloach, J., Chen, B.B., Nadakal, S., Highsmith, K., Ouahes, T., Conteh, S., Sharma, A., Torano, H., Butler, B., Reiter, K., Rausch, K.M., Scaria, P.V., Anderson, C., Narum, D.L., Salanti, A., Fried, M., Theander, T.G., Gamain, B., Duffy, P.E., (2023). Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA. Lab Anim [6.9] 1–9. doi: 10.1038/s41684-023-01274-2

Fernandes, P., Loubens, M., Marinach, C., Coppée, R., Baron, L., Grand, M., Andre, T.-P., Hamada, S., Langlois, A.-C., Briquet, S., Bun, P., Silvie, O., (2023). Plasmodium sporozoites require the protein B9 to invade hepatocytes. iScience [6.1] 26, 106056. doi: 10.1016/j.isci.2023.106056

Green, E., Jaouen, E., Klug, D., Olmo, R.P., Gautier, A., Blandin, S., Marois, E., (2023). A population modification gene drive targeting both Saglin and Lipophorin impairs Plasmodium transmission in Anopheles mosquitoes. bioRxiv [preprint] 2022.07.08.499187. doi: 10.1101/2022.07.08.499187

Hervé, P., Monic, S., Bringaud, F., Rivière, L., (2023). Phospholipases A and Lysophospholipases in protozoan parasites. Microb Cell [4.6] 10, 204–216. doi: 10.15698/mic2023.10.805

Hou, M.M., Barrett, J.R., Themistocleous, Y., Rawlinson, T.A., Diouf, A., Martinez, F.J., Nielsen, C.M., Lias, A.M., King, L.D.W., Edwards, N.J., Greenwood, N.M., Kingham, L., Poulton, I.D., Khozoee, B., Goh, C., Hodgson, S.H., Mac Lochlainn, D.J., Salkeld, J., Guillotte-Blisnick, M., Huon, C., Mohring, F., Reimer, J.M., Chauhan, V.S., Mukherjee, P., Biswas, S., Taylor, I.J., Lawrie, A.M., Cho, J.-S., Nugent, F.L., Long, C.A., Moon, R.W., Miura, K., Silk, S.E., Chitnis, C.E., Minassian, A.M., Draper, S.J., (2023). Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection. Sci Transl Med [19.3] 15, eadf1782. doi: 10.1126/scitranslmed.adf1782

Issa, M.S., Warsame, M., Mahamat, M.H.T., Saleh, I.D.M., Boulotigam, K., Djimrassengar, H., Issa, A.H., Abdelkader, O., Hassoumi, M., Djimadoum, M., Doderer-Lang, C., Ndihiokubwayo, J.B., Rasmussen, C., Menard, D., (2023). Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance. Malar J [3.5] 22, 240. doi: 10.1186/s12936-023-04644-w

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2022

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Ashraf, K., Tajeri, S., Arnold, C.-S., Amanzougaghene, N., Franetich, J.-F., Vantaux, A., Soulard, V., Bordessoulles, M., Cazals, G., Bousema, T., Gemert, G.-J. van, Grand, R.L., Dereuddre-Bosquet, N., Barale, J.-C., Witkowski, B., Snounou, G., Duval, R., Botté, C.Y., Mazier, D., (2022). Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites. Life Sci Alliance [4.6] 5. doi: 10.26508/lsa.202101237

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Croce, C., Garrido, F., Dinamarca, S., Santi-Rocca, J., Marion, S., Blanchard, N., Mayorga, L.S., Cebrian, I., (2022). Efficient Cholesterol Transport in Dendritic Cells Defines Optimal Exogenous Antigen Presentation and Toxoplasma gondii Proliferation. Front Cell Dev Biol [6.7] 10. doi: 10.3389/fcell.2022.837574

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Hakimi, M.-A., (2022). Epigenetic Reprogramming in Host-Parasite Coevolution: The Toxoplasma Paradigm. Annu Rev Microbiol [15.5] 76, annurev-micro-041320-011520. doi: 10.1146/annurev-micro-041320-011520

Hassan, A., Blanchard, N., (2022). Microbial (co)infections: Powerful immune influencers. PLoS Pathog [6.8] 18, e1010212. doi: 10.1371/journal.ppat.1010212

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Klug, D., Arnold, K., Mela-Lopez, R., Marois, E., Blandin, S.A., (2022). A toolbox of engineered mosquito lines to study salivary gland biology and malaria transmission. PLoS Pathog [6.8] 18, e1010881. doi: 10.1371/journal.ppat.1010881

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Leleu, I., Alloo, J., Cazenave, P.-A., Roland, J., Pied, S., (2022). Autophagy Pathways in the Genesis of Plasmodium-Derived Microvesicles: A Double-Edged Sword? Life [3.8] 12, 415. doi: 10.3390/life12030415

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Manickam, Y., Malhotra, N., Mishra, S., Babbar, P., Dusane, A., Laleu, B., Bellini, V., Hakimi, M.-A., Bougdour, A., Sharma, A., (2022). Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development. PLoS Pathog [6.8] 18, e1010363. doi: 10.1371/journal.ppat.1010363

Monic, S.G., Lamy, A., Thonnus, M., Bizarra-Rebelo, T., Bringaud, F., Smith, T.K., Figueiredo, L.M., Rivière, L., (2022). A novel lipase with dual localisation in Trypanosoma brucei. Sci Rep [4.4] 12, 4766. doi: 10.1038/s41598-022-08546-w

Mwakasungula, S., Rougeron, V., Arnathau, C., Boundenga, L., Miguel, E., Boissière, A., Jiolle, D., Durand, P., Msigwa, A., Mswata, S., Olotu, A., Sterkers, Y., Roche, B., Killeen, G., Cerqueira, F., Bitome-Essono, P.Y., Bretagnolle, F., Masanja, H., Paupy, C., Sumaye, R., Prugnolle, F., (2022). Using hematophagous fly blood meals to study the diversity of blood-borne pathogens infecting wild mammals. Mol Ecol Resour [7.1]. doi: 10.1111/1755-0998.13670

Najm, R., Hamie, M., Berry-Sterkers, L., Lebrun, M., El Hajj, H., Lamarque, M.H., (2022). Toxoplasma Shelph, a Phosphatase Located in the Parasite Endoplasmic Reticulum, Is Required for Parasite Virulence. mSphere [5.0] e00350-22. doi: 10.1128/msphere.00350-22

Negreira, G.H., Monsieurs, P., Imamura, H., Maes, I., Kuk, N., Yagoubat, A., Van den Broeck, F., Sterkers, Y., Dujardin, J.-C., Domagalska, M.A., (2022). High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani. Nucleic Acids Res [17.0] 50, 293–305. doi: 10.1093/nar/gkab1203

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Shunmugam, S., Arnold, C.-S., Dass, S., Katris, N.J., Botté, C.Y., (2022). The flexibility of Apicomplexa parasites in lipid metabolism. PLoS Pathog [6.8] 18, e1010313. doi: 10.1371/journal.ppat.1010313

Silvestre, A., Shintre, S.S., Rachidi, N., (2022). Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies. Front Cell Infect Microbiol [5.3] 12, 825458. doi: 10.3389/fcimb.2022.825458

Sparvoli, D., Delabre, J., Penarete‐Vargas, D.M., Kumar Mageswaran, S., Tsypin, L.M., Heckendorn, J., Theveny, L., Maynadier, M., Mendonça Cova, M., Berry‐Sterkers, L., Guérin, A., Dubremetz, J., Urbach, S., Striepen, B., Turkewitz, A.P., Chang, Y., Lebrun, M., (2022). An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma. Embo J [13.8]al. doi: 10.15252/embj.2022111158

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Tajeri, S., Momeux, L., Saintpierre, B., Mfarrej, S., Chapple, A., Mourier, T., Shiels, B., Ariey, F., Pain, A., Langsley, G., (2022). Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion. Sci Rep [5.0] 12, 12710. doi: 10.1038/s41598-022-15518-7

ten Hoeve, A.L., Braun, L., Rodriguez, M.E., Olivera, G.C., Bougdour, A., Belmudes, L., Couté, Y., Saeij, J.P.J., Hakimi, M.-A., Barragan, A., (2022). The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages. Cell Host Microbe [31.3] S1931312822005121. doi: 10.1016/j.chom.2022.10.001

Trindade, S., De Niz, M., Costa-Sequeira, M., Bizarra-Rebelo, T., Bento, F., Dejung, M., Narciso, M.V., López-Escobar, L., Ferreira, J., Butter, F., Bringaud, F., Gjini, E., Figueiredo, L.M., (2022). Slow growing behavior in African trypanosomes during adipose tissue colonization. Nat Commun [17.7] 13, 7548. doi: 10.1038/s41467-022-34622-w

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Wagner, M.P., Formaglio, P., Gorgette, O., Dziekan, J.M., Huon, C., Berneburg, I., Rahlfs, S., Barale, J.-C., Feinstein, S.I., Fisher, A.B., Ménard, D., Bozdech, Z., Amino, R., Touqui, L., Chitnis, C.E., (2022). Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target. Cell Rep [9.4] 39, 110923. doi: 10.1016/j.celrep.2022.110923

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2019

Allmann, S., Wargnies, M., Cahoreau, E., Biran, M., Plazolles, N., Morand, P., Pineda, E., Kulyk, H., Asencio, C., Villafraz, O., Rivière, L., Tétaud, E., Rotureau, B., Mourier, A., Portais, J.-C., Bringaud, F., (2019). “Metabolic contest”, a new way to control carbon source preference. bioRxiv [preprint] 800839. doi:10.1101/800839

Amiar, S., Katris, N.J., Berry, L., Dass, S., Shears, M.J., Brunet, C., Touquet, B., Hakimi, M.-A., McFadden, G.I., Yamaryo-Botté, Y., Botté, C.Y., (2019). Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling. bioRxiv [preprint]. doi:10.1101/585737

Asad, M., Yamaryo-Botté, Y., Hossain, M.E., Thakur, V., Jain, S., Datta, G., Botté, C.Y., Mohmmed, A., (2019). A lysophospholipase plays role in generation of neutral-lipids required for hemozoin formation in malaria parasite. bioRxiv [preprint]. doi:10.1101/808709

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Baumgarten, S., Bryant, J.M., Sinha, A., Reyser, T., Preiser, P.R., Dedon, P.C., Scherf, A., (2019). Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development. Nat Microbiol [14.2] 4, 2246–2259. doi:10.1038/s41564-019-0521-7

Beri, D., Ramdani, G., Balan, B., Gadara, D., Poojary, M., Momeux, L., Tatu, U., Langsley, G., (2019). Insights into physiological roles of unique metabolites released from Plasmodium-infected RBCs and their potential as clinical biomarkers for malaria. Sci Rep [4.1] 9, 2875. doi:10.1038/s41598-018-37816-9

Besteiro, S., (2019). The role of host autophagy machinery in controlling Toxoplasma infection. Virulence [4.8] 10, 438–447. doi:10.1080/21505594.2018.1518102

Braun, L., Brenier-Pinchart, M.P., Hammoudi, P.M., Cannella, D., Kieffer-Jaquinod, S., Vollaire, J., Josserand, V., Touquet, B., Coute, Y., Tardieux, I., Bougdour, A., Hakimi, M.A., (2019). The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kappaB signalling via EZH2. Nat Microbiol [14.2]. doi:10.1038/s41564-019-0431-8

Cotos, L., Donzel, M., Elhabiri, M., Davioud-Charvet, E., (2019). A Mild and Versatile Friedel-Crafts Methodology for the Diversity-Oriented Synthesis of Redox-Active 3-Benzoylmenadiones with Tuneable Redox Potentials. Chem-Eur J [5.2]. doi:10.1002/chem.201904220

Courtois, P., Nabos, P., Nzoumbou-Boko, R., Reix, C.E., Dauchy, F.-A., Daulouede, S., Bringaud, F., Robinson, D.R., Vincendeau, P., (2019). Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns). JoVE [1.2] e58415. doi:doi:10.3791/58415

Dauchy, F.A., Contin-Bordes, C., Nzoumbou-Boko, R., Bonhivers, M., Landrein, N., Robinson, D.R., Rambert, J., Courtois, P., Daulouede, S., Vincendeau, P., (2019). Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide-induced maturation and activation of human monocyte-derived dendritic cells. Parasite Immunol [2.8] 41, e12632. doi:10.1111/pim.12632

Deloule, V., Boisset, C., Hannani, D., Suau, A., Le Gouellec, A., Chroboczek, J., Botté, C., Yamario-Botté, Y., Chirat, C., Toussaint, B., (2019). Prebiotic role of softwood hemicellulose in healthy mice model. J Funct Foods [3.2] 103688. doi:10.1016/j.jff.2019.103688

Demarta-Gatsi, C., Rivkin, A., Di Bartolo, V., Peronet, R., Ding, S., Commere, P.-H., Guillonneau, F., Bellalou, J., Brûlé, S., Abou Karam, P., Cohen, S.R., Lagache, T., Janse, C.J., Regev-Rudzki, N., Mécheri, S., (2019). Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses. Cell Microbiol [4.4] 0, e13021. doi:10.1111/cmi.13021

Dorin-Semblat, D., Tetard, M., Claes, A., Semblat, J.P., Dechavanne, S., Fourati, Z., Hamelin, R., Armand, F., Matesic, G., Nunes-Silva, S., Srivastava, A., Gangnard, S., Lopez-Rubio, J.J., Moniatte, M., Doerig, C., Scherf, A., Gamain, B., (2019). Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA. PLoS Biol [8.4] 17, e3000308. doi:10.1371/journal.pbio.3000308

Fernandes, P.M., Kinkead, J., McNae, I.W., Bringaud, F., Michels, P.A.M., Walkinshaw, M.D., (2019). The kinetic characteristics of human and Trypanosomatid phosphofructokinases for the reverse reaction. Biochem J [3.9] 476, 179–191. doi:10.1042/BCJ20180635

Florini, F., Naguleswaran, A., Gharib, W.H., Bringaud, F., Roditi, I., (2019). Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. Nucleic Acids Res [11.2] 47, 1725–1739. doi:10.1093/nar/gky1255

Fox, B.A., Guevara, R.B., Rommereim, L.M., Falla, A., Bellini, V., Petre, G., Rak, C., Cantillana, V., Dubremetz, J.F., Cesbron-Delauw, M.F., Taylor, G.A., Mercier, C., Bzik, D.J., (2019). Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon. mBio [6.7] 10, e00589-19. doi:10.1128/mBio.00589-19

Guillen, N., (2019). The interaction between Entamoeba histolytica and enterobacteria shed light on an ancient antibacterial response. Cell Microbiol [4.4] 0, e13039. doi:10.1111/cmi.13039

Haidar, M., Metheni, M., Batteux, F., Langsley, G., (2019). TGF-beta2, catalase activity, H2O2 output and metastatic potential of diverse types of tumour. Free Radic Biol Med [6.0] 134, 282–287. doi:10.1016/j.freeradbiomed.2019.01.010

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Hassan, A., Wlodarczyk, M.F., Benamar, M., Bassot, E., Salvioni, A., Kassem, S., Berry, A., Saoudi, A., Blanchard, N., (2019). A virus hosted in malaria-infected blood protects against T cell-mediated inflammatory diseases by impairing DC function in a type I IFN-dependent manner. bioRxiv [preprint] 830687. doi:10.1101/830687

Hernandez-Cuevas, N.A., Jhingan, G.D., Petropolis, D., Vargas, M., Guillen, N., (2019). Acetylation is the most abundant actin modification in Entamoeba histolytica and modifications of actin’s amino-terminal domain change cytoskeleton activities. Cell Microbiol [4.4] 21, e12983. doi:10.1111/cmi.12983

Herrera‐Solorio, A.M., Vembar, S.S., MacPherson, C.R., Lozano‐Amado, D., Meza, G.R., Xoconostle‐Cazares, B., Martins, R.M., Chen, P., Vargas, M., Scherf, A., Hernández‐Rivas, R., (2019). Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite <em>Plasmodium falciparum</em>. EMBO reports [8.7] 20, e46331. doi:10.15252/embr.201846331

Jamonneau, V., Truc, P., Grébaut, P., Herder, S., Ravel, S., Solano, P., De Meeus, T., (2019). Trypanosoma brucei gambiense Group 2: The Unusual Suspect. Trends in Parasitology. doi:10.1016/j.pt.2019.09.002

Keswani, T., Roland, J., Herbert, F., Delcroix-Genete, D., Bauderlique-Le Roy, H., Gaayeb, L., Cazenave, P.-A., Pied, S., (2019). Expression of CD300lf by microglia contributes to resistance to cerebral malaria by impeding the neuroinflammation. Genes Immun. doi:10.1038/s41435-019-0085-9

Latre de Late, P., Haidar, M., Ansari, H., Tajeri, S., Szarka, E., Alexa, A., Woods, K., Remenyi, A., Pain, A., Langsley, G., (2019). Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104. Cell Microbiol [4.4] 21, e12973. doi:10.1111/cmi.12973

Lee, M.C.S., Lindner, S.E., Lopez-Rubio, J.J., Llinas, M., (2019). Cutting back malaria: CRISPR/Cas9 genome editing of Plasmodium. Brief Funct Genomics [3.1]. doi:10.1093/bfgp/elz012

Lejon, V., Buscher, P., Nzoumbou-Boko, R., Bossard, G., Jamonneau, V., Bucheton, B., Truc, P., Lemesre, J.L., Solano, P., Vincendeau, P., (2019). The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham’s discovery 50 years ago to a gold standard for sleeping sickness diagnosis. PLoS Negl Trop Dis [3.8] 13, e0007051. doi:10.1371/journal.pntd.0007051

Loeuillet, C., Mondon, A., Kamche, S., Curri, V., Boutonnat, J., Cavailles, P., Cesbron-Delauw, M.F., (2019). Toxoplasma Hypervirulence in the Rat Model Parallels Human Infection and Is Modulated by the Toxo1 Locus. Front Cell Infect Microbiol [3.5] 9, 134. doi:10.3389/fcimb.2019.00134

Lorès, P., Dacheux, D., Kherraf, Z.-E., Nsota Mbango, J.-F., Coutton, C., Stouvenel, L., Ialy-Radio, C., Amiri-Yekta, A., Whitfield, M., Schmitt, A., Cazin, C., Givelet, M., Ferreux, L., Fourati Ben Mustapha, S., Halouani, L., Marrakchi, O., Daneshipour, A., El Khouri, E., Do Cruzeiro, M., Favier, M., Guillonneau, F., Chaudhry, M., Sakheli, Z., Wolf, J.-P., Patrat, C., Gacon, G., Savinov, S.N., Hosseini, S.H., Robinson, D.R., Zouari, R., Ziyyat, A., Arnoult, C., Dulioust, E., Bonhivers, M., Ray, P.F., Touré, A., (2019). Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility. The American Journal of Human Genetics. doi:10.1016/j.ajhg.2019.10.007

Marozienė, A., Lesanavičius, M., Davioud-Charvet, E., Aliverti, A., Grellier, P., Šarlauskas, J., Čėnas, N., (2019). Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase. Molecules [3.1] 24, 4509. doi:10.3390/molecules24244509

Martin-Benlloch, X., Haid, S., Novodomska, A., Rominger, F., Pietschmann, T., Davioud-Charvet, E., Elhabiri, M., (2019). Physicochemical Properties Govern the Activity of Potent Antiviral Flavones. ACS Omega [2.6] 4, 4871–4887. doi:10.1021/acsomega.8b03332

Mazier, D., Paris, L., (2019). Maladies parasitaires : vous avez dit « éradiquer » ? Med Sci (Paris) 35, 723–724. doi:10.1051/medsci/2019171

Mounkoro, P., Michel, T., Blandin, S., Golinelli-Cohen, M.P., Davioud-Charvet, E., Meunier, B., (2019). Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model. Free Radic Biol Med [5.7] 141, 269–278. doi:10.1016/j.freeradbiomed.2019.06.026

Nardella, F., Halby, L., Hammam, E., Erdmann, D., Cadet-Daniel, V., Peronet, R., Ménard, D., Witkowski, B., Mecheri, S., Scherf, A., Arimondo, P.B., (2019). DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites. ACS Cent. Sci. doi:10.1021/acscentsci.9b00874

Rchiad, Z., Haidar, M., Ansari, H.R., Tajeri, S., Mfarrej, S., Rached, F.B., Kaushik, A., Langsley, G., Pain, A., (2019). Novel tumor suppressor roles for GZMAand RASGRP1 in dissemination of both Theileria annulatatransformed macrophages and human B-lymphoma cells. bioRxiv [preprint] 338160. doi:10.1101/338160

Salvioni, A., Belloy, M., Lebourg, A., Bassot, E., Cantaloube-Ferrieu, V., Vasseur, V., Blanié, S., Liblau, R.S., Suberbielle, E., Robey, E.A., Blanchard, N., (2019). Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons. Cell Rep [7.8] 27, 3254-3268.e8. doi:10.1016/j.celrep.2019.05.051

Semenovskaya, K., Lévêque, M.F., Berry, L., Bordat, Y., Dubremetz, J.-F., Lebrun, M., Besteiro, S., (2019). TgZFP2 is a novel zinc finger protein involved in coordinating mitosis and budding in Toxoplasma. Cell Microbiol [4.4] 0, e13120. doi:10.1111/cmi.13120

Suarez, C., Lentini, G., Ramaswamy, R., Maynadier, M., Aquilini, E., Berry-Sterkers, L., Cipriano, M., Chen, A.L., Bradley, P., Striepen, B., Boulanger, M.J., Lebrun, M., (2019). A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nat Commun [11.9] 10, 4041. doi:10.1038/s41467-019-11979-z

Swale, C., Bougdour, A., Gnahoui-David, A., Tottey, J., Georgeault, S., Laurent, F., Palencia, A., Hakimi, M.-A., (2019). Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med [17.2] 11, eaax7161. Doi: 10.1126/scitranslmed.aax7161

Szöőr, B., Simon, D.V., Rojas, F., Young, J., Robinson, D.R., Krüger, T., Engstler, M., Matthews, K.R., (2019). Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation. MBio 10. doi:10.1128/mBio.00875-19

van der Laan, S., Lévêque, M., Marcellin, G., Vezenkov, L., Lannay, Y., Dubra, G., Bompard, G., Ovejero, S., Urbach, S., Burgess, A., Amblard, M., Sterkers, Y., Bastien, P., Rogowski, K., (2019). Evolutionary Divergence of Enzymatic Mechanisms for Tubulin Detyrosination. Cell Reports [7.8]. doi:10.1016/j.celrep.2019.11.074

Venugopal, K., Chehade, S., Werkmeister, E., Barois, N., Periz, J., Lafont, F., Tardieux, .I, Khalife, J., Langsley, G., Meissner, M., Marion, S. (2019). Rab11A regulates the constitutive secretory pathway during Toxoplasma gondii invasion of host cells and parasite replication. bioRxiv [preprint] 782391. doi:10.1101/782391

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Vidilaseris, K., Landrein, N., Pivovarova, Y., Lesigang, J., Aeksiri, N., Robinson, D.R., Bonhivers, M., Dong, G., (2019). Crystal structure of the TbBILBO1 N-terminal domain reveals a ubiquitin fold with a long rigid loop for the binding of its partner. bioRxiv [preprint] 738153. doi:10.1101/738153

Vidilaseris, K., Landrein, N., Pivovarova, Y., Lesigang, J., Aeksiri, N., Robinson, D.R., Bonhivers, M., Dong, G., (2019). Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding. J Biol Chem [4.1] jbc.RA119.010768. doi:10.1074/jbc.RA119.010768

2018

Abah, S.E., Burte, F., Marquet, S., Brown, B.J., Akinkunmi, F., Oyinloye, G., Afolabi, N.K., Omokhodion, S., Lagunju, I., Shokunbi, W.A., Wahlgren, M., Dessein, H., Argiro, L., Dessein, A.J., Noyvert, B., Hunt, L., Elgar, G., Sodeinde, O., Holder, A.A., Fernandez-Reyes, D., (2018). Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis. Sci Rep [4.1] 8, 17527. doi:10.1038/s41598-018-35944-w

Aliprandini, E., Tavares, J., Panatieri, R.H., Thiberge, S., Yamamoto, M.M., Silvie, O., Ishino, T., Yuda, M., Dartevelle, S., Traincard, F., Boscardin, S.B., Amino, R., (2018). Cytotoxic anti-circumsporozoite antibodies target malaria sporozoites in the host skin. Nat Microbiol [14.2] 3, 1224–1233. doi:10.1038/s41564-018-0254-z

Belmonte-Reche, E., Martinez-Garcia, M., Guedin, A., Zuffo, M., Arevalo-Ruiz, M., Doria, F., Campos-Salinas, J., Maynadier, M., Lopez-Rubio, J.J., Freccero, M., Mergny, J.L., Perez-Victoria, J.M., Morales, J.C., (2018). G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents. J Med Chem [6.3] 61, 1231–1240. doi:10.1021/acs.jmedchem.7b01672

Berry, L., Chen, C.T., Francia, M.E., Guerin, A., Graindorge, A., Saliou, J.M., Grandmougin, M., Wein, S., Bechara, C., Morlon-Guyot, J., Bordat, Y., Gubbels, M.J., Lebrun, M., Dubremetz, J.F., Daher, W., (2018). Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell Mol Life Sci [6.7] 75, 4417–4443. doi:10.1007/s00018-018-2889-6

Bosson-Vanga, H., Franetich, J.F., Soulard, V., Sossau, D., Tefit, M., Kane, B., Vaillant, J.C., Borrmann, S., Muller, O., Dereuddre-Bosquet, N., Le Grand, R., Silvie, O., Mazier, D., (2018). Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium. Malar J [2.7] 17, 143. doi:10.1186/s12936-018-2300-y

Botte, C.Y., McFadden, G.I., Yamaryo-Botte, Y., (2018). Isolating the Plasmodium falciparum Apicoplast Using Magnetic Beads. Methods Mol Biol [1.9], Plastids: Methods and Protocols 1829, 205–212.

Botte, C.Y., Yamaryo-Botte, Y., (2018). Complex Endosymbioses II: The Nonphotosynthetic Plastid of Apicomplexa Parasites (The Apicoplast) and Its Integrated Metabolism. Methods Mol Biol [1.9] 1829, 37–54. doi:10.1007/978-1-4939-8654-5_3

Bruening, J., Lasswitz, L., Banse, P., Kahl, S., Marinach, C., Vondran, F.W., Kaderali, L., Silvie, O., Pietschmann, T., Meissner, F., Gerold, G., (2018). Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PLoS Pathog [6.6] 14, e1007111. doi:10.1371/journal.ppat.1007111

Bryant, J.M., Baumgarten, S., Lorthiois, A., Scheidig-Benatar, C., Claes, A., Scherf, A., (2018). De Novo Genome Assembly of a Plasmodium falciparum NF54 Clone Using Single-Molecule Real-Time Sequencing. Genome Announc [no IF] 6. doi:10.1128/genomeA.01479-17

Buscher, P., Bart, J.M., Boelaert, M., Bucheton, B., Cecchi, G., Chitnis, N., Courtin, D., Figueiredo, L.M., Franco, J.R., Grebaut, P., Hasker, E., Ilboudo, H., Jamonneau, V., Koffi, M., Lejon, V., MacLeod, A., Masumu, J., Matovu, E., Mattioli, R., Noyes, H., Picado, A., Rock, K.S., Rotureau, B., Simo, G., Thevenon, S., Trindade, S., Truc, P., Van Reet, N., (2018). Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? Trends in parasitology 34, 197–207. doi:10.1016/j.pt.2017.11.008

Chevillard, C., Nunes, J.P.S., Frade, A.F., Almeida, R.R., Pandey, R.P., Nascimento, M.S., Kalil, J., Cunha-Neto, E., (2018). Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy. Front Immunol [5.5] 9, 2791. doi:10.3389/fimmu.2018.02791

Claessens, A., Harris, L.M., Stanojcic, S., Chappell, L., Stanton, A., Kuk, N., Veneziano-Broccia, P., Sterkers, Y., Rayner, J.C., Merrick, C.J., (2018). RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. PLoS Genet [6.1] 14, e1007490. doi:10.1371/journal.pgen.1007490

Coutton, C., Vargas, A.S., Amiri-Yekta, A., Kherraf, Z.E., Ben Mustapha, S.F., Le Tanno, P., Wambergue-Legrand, C., Karaouzene, T., Martinez, G., Crouzy, S., Daneshipour, A., Hosseini, S.H., Mitchell, V., Halouani, L., Marrakchi, O., Makni, M., Latrous, H., Kharouf, M., Deleuze, J.F., Boland, A., Hennebicq, S., Satre, V., Jouk, P.S., Thierry-Mieg, N., Conne, B., Dacheux, D., Landrein, N., Schmitt, A., Stouvenel, L., Lores, P., El Khouri, E., Bottari, S.P., Faure, J., Wolf, J.P., Pernet-Gallay, K., Escoffier, J., Gourabi, H., Robinson, D.R., Nef, S., Dulioust, E., Zouari, R., Bonhivers, M., Toure, A., Arnoult, C., Ray, P.F., (2018). Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human. Nat Commun [12.1] 9, 686. doi:10.1038/s41467-017-02792-7

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Dubois, D., Fernandes, S., Amiar, S., Dass, S., Katris, N.J., Botte, C.Y., Yamaryo-Botte, Y., (2018). Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages. J Lipid Res [4.8] 59, 994–1004. doi:10.1194/jlr.M082891

Eyssen, L.E., Vather, P., Jackson, L., Ximba, P., Biteau, N., Baltz, t., Boulange, A., Buscher, P., Coetzer, T.H.T., (2018). Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis. Molecular and Biochemical Parasitology 223, 50–54. doi:10.1016/j.molbiopara.2018.07.001

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2013

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Ammar, Z., Plazolles, N., Baltz, t., Coustou, V., (2013). Identification of trans-sialidases as a common mediator of endothelial cell activation by African trypanosomes. PLoS Pathog [8.1] 9, e1003710. doi:10.1371/journal.ppat.1003710

Azzouz, N., Kamena, F., Laurino, P., Kikkeri, R., Mercier, C., Cesbron-Delauw, M.F., Dubremetz, J.F., De Cola, L., Seeberger, P.H., (2013). Toxoplasma gondii secretory proteins bind to sulfated heparin structures. Glycobiology [3.7] 23, 106–20. doi:10.1093/glycob/cws134

Belorgey, D., Lanfranchi, D.A., Davioud-Charvet, E., (2013). 1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents. Curr Pharm Des [3.3] 19, 2512–28. doi:10.2174/1381612811319140003

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Caldarelli, S.A., El Fangour, S., Wein, S., Tran van Ba, C., Perigaud, C., Pellet, A., Vial, H.J., Peyrottes, S., (2013). New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation. J Med Chem [5.3] 56, 496–509. doi:10.1021/jm3014585

Davioud-Charvet, E., (2013). Opinion on “Drug Discovery in Infectious Diseases, Volume 3: Parasitic Helminths: Targets, Screens, Drugs and Vaccines. Edited by Conor R. Caffrey.” ChemMedChem [3.2] 8, 164–166. doi:10.1002/cmdc.201200515

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Gendron, T., Lanfranchi, D.A., Davioud-Charvet, E., (2013). Redox-Active Agents in Reactions Involving the Trypanothione/Trypanothione Reductase-based System to Fight Kinetoplastidal Parasites, in: Flohė, L., Jäger, T., Koch, O. (Eds.), Trypanosomatid Diseases: Molecular Routes to Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, pp. 405–428. doi:10.1002/9783527670383.ch22

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Lamacchia, M., Clayton, J.R., Wang-Sattler, R., Steinmetz, L.M., Levashina, E.A., Blandin, S.A., (2013). Silencing of Genes and Alleles by RNAi in Anopheles gambiae, in: Ménard, R. (Ed.), Malaria: Methods and Protocols, Methods in Molecular Biology. Humana Press, Totowa, NJ, pp. 161–176. doi:10.1007/978-1-62703-026-7_11

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Nagy, G.N., Marton, L., Kramos, B., Olah, J., Revesz, A., Vekey, K., Delsuc, F., Hunyadi-Gulyas, E., Medzihradszky, K.F., Lavigne, M., Vial, H., Cerdan, R., Vertessy, B.G., (2013). Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum. FEBS J [4.0] 280, 3132–48. doi:10.1111/febs.12282

Nzoumbou-Boko, R., Dethoua, M., Gabriel, F., Buguet, A., Cespuglio, R., Courtois, P., Daulouede, S., Bouteille, B., Ngampo, S., Mpandzou, G., Semballa, S., Vincendeau, P., (2013). Serum arginase, a biomarker of treatment efficacy in human African trypanosomiasis. J Clin Microbiol [4.2] 51, 2379–81. doi:10.1128/JCM.03371-12

Perdomo, D., Baron, B., Rojo-Dominguez, A., Raynal, B., England, P., Guillen, N., (2013). The alpha-helical regions of KERP1 are important in Entamoeba histolytica adherence to human cells. Sci Rep [5.1] 3, 1171. doi:10.1038/srep01171

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Pillay, D., Boulange, A.F., Coustou, V., Baltz, t., Coetzer, T.H., (2013a). Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense. Exp Parasitol [1.9] 135, 675–84. doi:10.1016/j.exppara.2013.10.005

Pillay, D., Izotte, J., Fikru, R., Buscher, P., Mucache, H., Neves, L., Boulange, A., Seck, M.T., Bouyer, J., Napier, G.B., Chevtzoff, C., Coustou, V., Baltz, t., (2013b). Trypanosoma vivax GM6 antigen: a candidate antigen for diagnosis of African animal trypanosomosis in cattle. PLoS One [3.5] 8, e78565. doi:10.1371/journal.pone.0078565

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French Alliance for Parasitology and Health Care

2018

PhD South Program

2015

2016

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Associate professor l Toxoplama l Bordeaux, France

EMBO Workshop Host Parasite 2025

ParaFrap Webinar - Gretchen DIFFENDALL

PostDoc x2 l Trypanosoma l Lisbon, PT

PostDoc l Trypanosoma l Paris, FR

PostDoc x2 l Malaria l Montpellier, FR

PostDoc l Leishmania l Paris, FR

Next Generation In Parasitology - Workshop

MA. Hakimi, laureate of the Excellence Chair in Biology/Health France 2030

Seminar - Boris Striepen - May 24

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