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Project Title : "Synthesis of chemical tools for tracking lead antiparasitic drugs and their metabolites generated in targeted parasites by nanoSIMS- and fluorescence confocal- imaging & metabolomics"
Project PI : Elisabeth Davioud-Charvet Co-PI : Stéphanie Blandin
Thesis defense : 11/07/2017
Lab : Laboratoire de Chimie Bioorganique et Médicinale, Strasbourg
POSITION AFTER PARAFRAP TRAINING
Postdoctoral researcher in Guangzhou, China
PUBLICATIONS
Cichocki, B.A., Donzel, M., Heimsch, K.C., Lesanavičius, M., Feng, L., Montagut, E.J., Becker, K., Aliverti, A., Elhabiri, M., Čėnas, N., Davioud-Charvet, E., (2021). Plasmodium falciparum Ferredoxin-NADP+ Reductase-Catalyzed Redox Cycling of Plasmodione Generates Both Predicted Key Drug Metabolites: Implication for Antimalarial Drug Development. ACS Infect Dis [4.6] doi: 10.1021/acsinfecdis.1c00054
Feng, L., Pomel, S., Latre de Late, P., Taravaud, A., Loiseau, P.M., Maes, L., Cho-Ngwa, F., Bulman, C.A., Fischer, C., Sakanari, J.A., Ziniel, P.D., Williams, D.L., Davioud-Charvet, E., (2020). Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections. Molecules [3.3] 25, 5075. doi: 10.3390/molecules25215075
Feng, L., D. A. Lanfranchi, L. Cotos, E. Cesar-Rodo, K. Ehrhardt, A.-A. Goetz, H. Zimmermann, F. Fenaille, S. A. Blandin and E. Davioud-Charvet (2018). "Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation." Org Biomol Chem [3.6] 16(15): 2647-2665. [Link]
Rodo, E. C., L. Feng, M. Jida, K. Ehrhardt, M. Bielitza, J. Boilevin, M. Lanzer, D. L. Williams, D. A. Lanfranchi and E. Davioud-Charvet (2016). "A Platform of Regioselective Methodologies to Access Polysubstituted 2-Methyl-1,4-naphthoquinone Derivatives: Scope and Limitations." European Journal of Organic Chemistry [3.1] 2016(11): 1982-1993 . [Link]
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