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French Alliance for Parasitology and Health Care

Home PhD 1ère vague Gigliola Zanghi
Zanghi

Project Title : "Investigations on the mechanisms of hypnozoite quiescence and activation in the malaria parasites Plasmodium vivax & P. cynomolgi"

Project PI : Dominique Mazier  Co-PI : Artur Scherf

Thesis defense : 01/12/2016 thesesfr

Lab : Malaria: identification and pre-clinical validation of novel therapeutics, CIMI, Paris

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BACKGROUND

  • Business Foundation Certificate, INSEA - France (2017)
  • Doctor in Industrial Pharmacy, University of Messina - Italy (2006-2011) 

POSITIONS AFTER PARAFRAP TRAINING

  • Postodoctoral researcher in Artur Scherf Lab, Pasteur Institute, Paris - France - (2017)
  • Postdoctoral researcher in Kappe Lab, Seattle Children's, USA (since 2018)

PUBLICATIONS

Zanghi, G., S. S. Vembar, S. Baumgarten, S. Ding, J. Guizetti, J. M. Bryant, D. Mattei, A. T. R. Jensen, L. Renia, Y. S. Goh, R. Sauerwein, C. C. Hermsen, J. F. Franetich, M. Bordessoulles, O. Silvie, V. Soulard, O. Scatton, P. Chen, S. Mecheri, D. Mazier and A. Scherf (2018). "A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection." Cell Rep [8.3] 22(11): 2951-2963. [Pubmed]

Cubi, R., S. S. Vembar, A. Biton, J. F. Franetich, M. Bordessoulles, D. Sossau, G. Zanghi, H. Bosson-Vanga, M. Benard, A. Moreno, N. Dereuddre-Bosquet, R. Le Grand, A. Scherf and D. Mazier (2017). "Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species." Cell Microbiol [4.5] 19(8). [Pubmed]

Chen, P. B., S. Ding, G. Zanghi, V. Soulard, P. A. DiMaggio, M. J. Fuchter, S. Mecheri, D. Mazier, A. Scherf and N. A. Malmquist (2016). "Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites." Sci Rep [5.2] 6: 21802. [Pubmed]

Barata, L., P. Houze, K. Boutbibe, G. Zanghi, J. F. Franetich, D. Mazier and J. Clain (2016). "In Vitro Analysis of the Interaction between Atovaquone and Proguanil against Liver Stage Malaria Parasites." Antimicrob Agents Chemother [4.5] 60(7): 4333-4335. [Pubmed]

Soulard, V., H. Bosson-Vanga, A. Lorthiois, C. Roucher, J. F. Franetich, G. Zanghi, M. Bordessoulles, M. Tefit, M. Thellier, S. Morosan, G. Le Naour, F. Capron, H. Suemizu, G. Snounou, A. Moreno-Sabater and D. Mazier (2015). "Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice." Nat Commun [11.5] 6: 7690. [Pubmed]
Monday, 15 May 2023

    Emerging Leader Research Fellow, Oxford Brookes University, UK  The Oxford Brookes University offers an opportunity to develop an independent research group in molecular parasitology/protistology through a...

Wednesday, 05 April 2023

PostDoc position : Gene regulation/ DNA low complexity regions-DNA binding proteins, Montpellier, France  The post-doc project aims to investigate the role of Low Complexity Regions in regulation of gene expression in P....

Monday, 03 April 2023

    Short-Term Scientific Missions (STSMs) within the OneHealthdrugs (CA21111) network 1st CALL for applications 2023  The 1st STSM Call of the Action CA2111 OneHealthdrugs is launched. Short Term Scientific Mission...

Tuesday, 28 March 2023

    PostDoc position : Cross-talk between stress response and infection in dendritic cells at Institut Pasteur Lille, France  We seek to hire a highly motivated candidate to work on the role of the Unfolded Protein...

Friday, 27 January 2023

[Publication] Les derniers travaux de Rania Najm, Hiba El Hajj, Maryse Lebrun & leurs collègues sont publiés dans PNAS. Les auteurs apportent des connaissances importantes sur les acteurs moléculaires de l'invasion des bradyzoïtes et...

Tuesday, 03 January 2023

LabEx ParaFrap wishes you happiness, health, science and success for 2023. First news from the network this year: the ParaFrap webinars will be back in 2023, as in previous years, every second Thursday of the month at 3pm. If you are not yet on the...

Friday, 16 December 2022

    PostDoc position in Biological Sciences / Biochemistry: Mode of action of antimalarial benzylmenadiones at IBMC, Strasbourg, France  A renewable 1-year postdoctoral position is open at IBMC (Inserm/CNRS/University...

Monday, 14 November 2022

[Communiqué] Gerald Spaeth, head of the "Molecular Parasitology and Signalling" unit at the Institut Pasteur Paris, has been awarded a Synergy grant from the European Research Council (ERC) for the project "DECOLeishRN - Decoding...

Monday, 10 October 2022

PostDoc position studying host-pathogen interactions at Institut Pasteur, Paris, France A postdoc position is available at the Institut Pasteur in the signalling and host-parasite interactions group, headed by Najma Rachidi, to investigate the...

Friday, 17 June 2022

[Communiqué] The team of Dr Chetan Chitnis from the Institut Pasteur, a partner in LabEx ParaFrap, has studied the blood stage of the Plasmodium falciparum parasite, which causes the most severe and deadly form of malaria, and discovered a...

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CONTACT

Project Manager: Yoann MILLERIOUX
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