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Une nouvelle cible médicamenteuse contre le paludisme
[Communiqué]
The team of Dr Chetan Chitnis from the Institut Pasteur, a partner in LabEx ParaFrap, has studied the blood stage of the Plasmodium falciparum parasite, which causes the most severe and deadly form of malaria, and discovered a mechanism that could lead to the development of new effective drugs against malaria. The results of this study were published in a communication of Institut Pasteur.
Work published in Cell Reports : Matthias Paulus Wagner, Pauline Formaglio, Olivier Gorgette, Jerzy Michal Dziekan, Christèle Huon, Isabell Berneburg, Stefan Rahlfs, Jean-Christophe Barale, Sheldon I. Feinstein, Aron B. Fisher, Didier Ménard, Zbynek Bozdech, Rogerio Amino, Lhousseine Touqui, Chetan E. Chitnis (2022) Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target. Cell Reports, Volume 39, Issue 11. doi: 10.1016/j.celrep.2022.110923.
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