Project Title : "Epigenetic Regulation of Chromosomal Replication in Leishmania "

Project PI : Yvon Sterkers (P. Bastien's group) Co-PI : Artur Scherf

Thesis defense : 20/12/2016 

Lab : Biologie, génétique et pathologie des pathogènes eucaryotes, Montpellier

BACKGROUND

• Engineer, university of Montpellier - France (2008-2013)
• Master's degree in Gene Expression and Recombinant Proteins, University Toulouse III - France (2007-2009)
• Bachelor's degree in Microbiology, University Blaise Pascal, Clermont-Ferrand - France (2004-2007)

POSITION AFTER PARAFRAP TRAINING

• Since 2022 : Research Assistant in Matthias Marti's lab, Institute of Parasitology, Zurich, Switzerland
• 2017-2021 : Postdoctoral researcher in Matthias Marti team, Wellcome Trust Center for Molecular Parasitology, University of Glasgow - Scotland

PUBLICATIONS

Vergnes, B., Gazanion, E., Mariac, C., Du Manoir, M., Sollelis, L., Lopez-Rubio, J.J., Sterkers, Y., Banuls, A.L., (2019). A single amino acid substitution (H451Y) in Leishmania calcium-dependent kinase SCAMK confers high tolerance and resistance to antimony. J Antimicrob Chemother [5.1]. doi: 10.1093/jac/dkz334

Garcia-Silva, M. R., L. Sollelis, C. R. MacPherson, S. Stanojcic, N. Kuk, L. Crobu, F. Bringaud, P. Bastien, M. Pages, A. Scherf and Y. Sterkers (2017). "Identification of the centromeres of Leishmania major: revealing the hidden pieces." EMBO Rep [8.7]. [Link] [PDF]

Stanojcic, S., L. Sollelis, N. Kuk, L. Crobu, Y. Balard, E. Schwob, P. Bastien, M. Pages and Y. Sterkers (2016). "Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells." Sci Rep [5.2] 6: 23142. [Pubmed] [PDF]

Sollelis, L., M. Ghorbal, C. R. MacPherson, R. M. Martins, N. Kuk, L. Crobu, P. Bastien, A. Scherf, J. J. Lopez-Rubio and Y. Sterkers (2015). "First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites." Cell Microbiol [4.8] 17(10): 1405-1412. [Pubmed] [PDF]